Sarcopenia is a disorder involving the loss of skeletal muscle mass and function that commonly occurs with advancing age and a number of long-term conditions. Recognition in clinical practice is relatively recent but important because sarcopenia has a variety of adverse health effects. Original definitions focused on, Simple summary. Sarcopenia is characterized by an accelerated decline in skeletal muscle mass and strength, resulting in poor quality of life, disability and death. In the literature, sarcopenia is defined as the progressive breakdown of muscle tissue. The prevalence ranges. in - old and. in. Sarcopenia is classically defined as the age-related decline in skeletal muscle mass and function. Rosenberg described progressive, generalized loss of SMM and a concomitant decline in function with increasing age. Rosenberg, 1997. Sarcopenia is intrinsic to the aging process but can be accelerated by various, Abstract. Sarcopenia is a loss of muscle mass and function in older adults that reduces mobility, decreases quality of life, and can lead to fall-related injuries, requiring expensive hospitalization and prolonged rehabilitation. This review focuses on structural changes and mechanisms related to aging at the cellular and subcellular levels. Objective The aim of this study was to perform a systematic review to evaluate the short, medium and long-term consequences of sarcopenia. Methods Prospective studies evaluating the consequences of sarcopenia were searched in various electronic databases MEDLINE, EMBASE, EBM Reviews, Cochrane Database, 1. Introduction. Sarcopenia was recognized as a disease, ICD-10-CM code M62.84, years after this term was coined and first mentioned by Irwin Rosenberg 1 and after important basic and clinical investigations. Its recognition as a disease resulting in reduced muscle mass and muscle strength, and low physique,